Journal of the American Chemical Society

Synthesis of a Substituted Phenylnaphthalene Related to Podophyllotoxin

W Reeve, H Myers

Index: Reeve; Myers Journal of the American Chemical Society, 1953 , vol. 75, p. 4957

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Citation Number: 5

Abstract

In attempting to synthesize one of the isomers of the podophyllotoxin-picropodophyllin series I, we have prepared a substituted l-phenylnaphthalene (111) differing from podophyllotoxin or picropodophyllin only in that it has a naphthalene ring instead of a tetralin ring, is a methyl ester in-stead of a lactone, and is missing a hydroxymethyl group.