An ecofriendly green approach for synthesis of substituted pyrano [2, 3-c] pyrazoles has been developed via a multicomponent one pot approach in aqueous ethanol medium under totally non-catalytic conditions. The synthesized compounds were evaluated for their antibacterial, anti-inflammatory and cytotoxic activities.
![(5R)-3-amino-7-methyl-5,9-diphenyl-2-oxa-8,9-diazabicyclo[4.3.0]nona-3,7,10-triene-4-carbonitrile Structure](https://image.chemsrc.com/caspic/331/53316-57-7.png)
![6-amino-3-methyl-4-(4-nitrophenyl)-1-phenyl-4H-pyrano[2,3-c]pyrazole-5-carbonitrile Structure](https://image.chemsrc.com/caspic/222/76973-34-7.png)
![Pyrano[2,3-c]pyrazole-5-carbonitrile,6-amino-1,4-dihydro-4-(4-methoxyphenyl)-3-methyl-1-phenyl- Structure](https://image.chemsrc.com/caspic/390/53316-60-2.png)