Tetrahedron letters

Facile desilylative hydroxyalkylation and acylation of 1-trimethylsilylmethyl-2-pyridone

AR Katritzky, S Sengupta

Index: Katritzky, Alan R.; Sengupta, Saumitra Tetrahedron Letters, 1987 , vol. 28, # 45 p. 5419 - 5422

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Citation Number: 17

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Department of Chemistry, University of Florida, Gainesville, FL 32611, USA. ... The title compound provides the first preparatively useful synthon for the α-carbanion of 1-methyl-2-pyridone. Desilylative hydroxyalkylation and acylation give the appropriate 1-(β-hydroxyalkyl) or 1-(β-oxoalkyl)-2 ...