Green Chemistry

Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

Y Wei, J Tang, X Cong, X Zeng

Index: Wei, Yu; Tang, Jinghua; Cong, Xuefeng; Zeng, Xiaoming Green Chemistry, 2013 , vol. 15, # 11 p. 3165 - 3169

Full Text: HTML

Citation Number: 13

Abstract

Metal-free synthesis of chalcone derivatives through a tandem cross-dehydrogenative- coupling/elimination reaction is described. A simple and inexpensive ammonium persulfate salt enables the reaction between ketones and benzylamines to proceed with high stereoselectivity and good functional group compatibility.