Synthesis of variously oxidized abietane diterpenes and their antibacterial activities against MRSA and VRE

…, Y Kitano, K Chiba, N Shibata, H Kurokawa…

Index: Yang, Zhixiang; Kitano, Yoshikazu; Chiba, Kazuhiro; Shibata, Naohiro; Kurokawa, Hiroshi; Doi, Yohei; Arakawa, Yoshichika; Tada, Masahiro Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 2 p. 347 - 356

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Citation Number: 77

Abstract

Variously oxidized 12 natural abietanes, 6, 7-dehydroferruginol methyl ether (3), ferruginol (5), 11-hydroxy-12-oxo-7, 9 (11), 13-abietatriene (7), royleanone (9), demethyl cryptojaponol (12), salvinolone (14), sugiol methyl ether (16), sugiol (17), 5, 6-dehydrosugiol methyl ether (19), 5, 6-dehydrosugiol (20), 6β-hydroxyferruginol (23), and taxodione (25) were synthesized. Antimicrobial activities of synthesized phenolic diterpenes and their related ...