Benzoyl cyanide: a mild and efficient reagent for benzoylation of nucleosides

…, V Kumar, J Maity, Z Wang, VT Ravikumar…

Index: Prasad, Ashok K.; Kumar, Vineet; Maity, Jyotirmoy; Wang, Zhiwei; Ravikumar, Vasulinga T.; Sanghvi, Yogesh S.; Parmar, Virinder S. Synthetic Communications, 2005 , vol. 35, # 7 p. 935 - 945

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Citation Number: 11

Abstract

Protecting groups play a pivotal role in the synthesis of nucleic acids, polypeptides, oligosaccharides, and natural products. One of the most frequently used protecting groups for the blocking of hydroxyl and amino functionalities of a compound is a benzoyl group. The classical method for benzoylation of hydroxyl and amino groups is the treatment of the substrate with benzoyl chloride/benzoic anhydride11. Schaller , H. , Weimann , G. , Lerch , B. and Khorana , HG ...