Abstract Crown ethers containing a thiazole subcyclic unit are prepared from the reactions of 1, 3-bis [2 (4-hydroxymethylthiazoyl)] benzene with di-p-tosylates of corresponding di, tri, tetra, pentaethylene glycols in the presence of potassium hydride. However, if the cavity size in the ring system is small,[2+ 2] cyclization adduct also is formed.