e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
1, 3, 2-Diazaphosphorine 2-Oxides. III. 1 Preparation and Biological Evaluation of Some 1, 3-Bis (aralkyl)-2-halo-1, 3, 2-diazaphosphorine 2-Oxides and Related …
JH Billman, JL Meisenheimer…
Index: Billman,J.H. et al. Journal of Medicinal Chemistry, 1966 , vol. 9, p. 772 - 774
Conipouiids oi tylr I1 n-cre the first to be syritlic5izcd 111 the hope of firidiiig a inore versatile routc to the 1.3-bis (aralkyl)-2-(S-nrylaniino)-l,~ 3, 2-diazaphos~~ lioriii~ 2-oxides (VIII) whivh have been of interest ns potential antitumor agents in this 1sboratory. l The original method used for iiialiirig these latter compounds involved the reaction of a dianiine (VI) with a phosphoramidic dichloride (YII), as shown below in Scheme 1V in the equation labeled ...
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