Practical and Chemoselective Reduction of Acyl Chloride to Alcohol by Borohydride in Aqueous Dichloromethane

R Rajan, S Badgujar, K Kaur, Y Malpani…

Index: Rajan, Ramya; Badgujar, Sachin; Kaur, Kamaljit; Malpani, Yashwardhan; Kanjilal, Pranab R. Synthetic Communications, 2010 , vol. 40, # 19 p. 2897 - 2907

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Citation Number: 5

Abstract

A simple methodology for the reduction of acid chlorides to their corresponding alcohols has been developed. Various carboxylic acids were converted to alcohols in excellent yields using NaBH4-K2CO3 in a mixed solvent system of dichloromethane and water (1: 1) in the ...