Tetrahedron

New chemo and chemo-enzymatic synthesis of β-benzyl-γ-butyrolactones

S Koul, B Singh, SC Taneja, GN Qazi

Index: Koul; Singh; Taneja; Qazi Tetrahedron, 2003 , vol. 59, # 19 p. 3487 - 3491

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Citation Number: 25

Abstract

β-Benzyl-γ-butyrolactones, important intermediates for the synthesis of butyrolactone lignans, have been synthesized by a new route involving preparation of α-β-unsaturated formyl esters. The formyl esters can easily be converted into the desired butyrolactones either through chemical transformations or by enzymatic methods.