Synthesis of 3-pyridyl-substituted 5-amino-1, 2, 4-triazoles from aminoguanidine and pyridinecarboxylic acids

VM Chernyshev, EV Tarasova, AV Chernysheva…

Index: Chernyshev; Tarasova; Chernysheva; Taranushich Russian Journal of Applied Chemistry, 2011 , vol. 84, # 11 p. 1890 - 1896

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Abstract

Abstract Effect of the molar ratio between reagents, temperature, and synthesis duration on the yield of 3-pyridylsubstituted 5-amino-1, 2, 4-triazoles in the reaction of aminoguanidine hydrochloride with pyridinecarboxylic acids under acid catalysis conditions was studied. A single-reactor method for synthesis of 3-pyridyl-substituted 5-amino-1, 2, 4-triazoles and their hydrochlorides was developed.