Abstract A series of 2-(2-hydrazinyl) thiazole derivatives with a wide range of substitutions at 2-, 4-and 5-positions were synthesized, characterized and evaluated their inhibitory potentials against plasmodium falciparum, NF54, by in vitro blood stage assay. The compounds, ethyl-4-methyl-2-[(E)-2-[1-(pyridin-2-yl) ethylidene] hydrazin-1-yl]-1, 3-thiazole- 5-carboxylate, 4d, and 1-{4-methyl-2-[(E)-2-[1-(pyridin-2-yl) ethylidene] hydrazin-1-yl]-1, 3- ...
