European journal of organic chemistry

Ionic Liquid as Catalyst and Reaction Medium–A Simple, Efficient and Green Procedure for Knoevenagel Condensation of Aliphatic and Aromatic Carbonyl …

BC Ranu, R Jana

Index: Ranu, Brindaban C.; Jana, Ranjan European Journal of Organic Chemistry, 2006 , # 16 p. 3767 - 3770

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Citation Number: 146

Abstract

Abstract The basic ionic liquid 1-butyl-3-methylimidazolium hydroxide,[bmIm] OH, efficiently catalyzes Knoevenagel condensation without requirement of any organic solvent. A wide range of aliphatic and aromatic aldehydes and ketones easily undergo condensations with diethyl malonate, malononitrile, ethyl cyanoacetate, malonic acid and ethyl acetoacetate. The reactions proceed at room temperature and are very fast (10–30 min). However, the ...