Gossypol, gossypolone, reduced gossypol and new Schiff's bases of racemic gossypol and gossypolone were extracted or synthesized. Their cytotoxic activities on KB human cancer cells were determined. Gossypolone and the ethylamine derivative of gossypolone were the most active compounds (IC50 in the micromolar range in both cases). The cytotoxicity of gossypol and gossypolone was increased when the tests were performed in the absence ...
![[2,2'-Binaphthalene]-1,1',6,6',7,7'-hexol,8,8'-bis[(dodecylimino)methyl]-3,3'-dimethyl-5,5'-bis(1-methylethyl)- Structure](https://image.chemsrc.com/caspic/062/5463-57-0.png)
![7-[1,6-dihydroxy-3-methyl-7-oxo-8-[(pentylamino)methylidene]-5-propan-2-yl-naphthalen-2-yl]-3,8-dihydroxy-6-methyl-1-[(pentylamino)methylidene]-4-propan-2-yl-naphthalen-2-one Structure](https://image.chemsrc.com/caspic/053/5422-60-6.png)
![2,2',3,3',4,4'-hexamethoxy-7,7'-dimethyl-5,5'-di(propan-2-yl)-2h,2'h-8,8'-binaphtho[1,8-bc]furan Structure](https://image.chemsrc.com/caspic/492/31591-07-8.png)