Chemical Communications 2010-02-14

Efficient synthesis of aminopyridine derivatives by copper catalyzed amination reactions.

Mohammed K Elmkaddem, Cédric Fischmeister, Christophe M Thomas, Jean-Luc Renaud

Index: Chem. Commun. (Camb.) 46(6) , 925-7, (2010)

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Abstract

A copper(i) catalyzed amination reaction utilizing aqueous ammonia and operating under mild conditions is presented. This method was employed for the efficient synthesis of various aminopyridine derivatives bearing electron withdrawing and electron donating groups.