e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
1, 4, 5, 8-Tetraacyl-1, 4, 5, 8-tetraazadecalins: Configurational and conformational analysis in the crystal and in solution: Structure and conformation of heterocycles-12
…, M Anteunis, U Shmueli, L Schleifer, H Shvo, B Fuchs
A series of 1, 4, 5, 8-tetraacyl-1, 4, 5, 8-tetraazadecalins was studied and found to exist in trans form in analogy with the parent system2. Only tetraacetyltetraazadecalin (TATAD) could be obtained in both trans and cis forms, which were investigated in detail by X-ray diffraction analysis and NMR techniques, trans-TATAD (8) occurs in the crystal in a centrosymmetric double twist-boat conformation whereas cis-TATAD (9) has one ring as a ...