Asymmetric Aerobic Oxidation of α??Hydroxy Acid Derivatives Catalyzed by Reusable, Polystyrene??Supported Chiral N??Salicylidene Oxidovanadium tert??Leucinates

SB Salunke, NS Babu, CT Chen

Index: Salunke, Santosh B.; Babu, N.Seshu; Chen, Chien-Tien Advanced Synthesis and Catalysis, 2011 , vol. 353, # 8 p. 1234 - 1240

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Citation Number: 19

Abstract

Abstract The direct immobilization of two different C-5-propargyl ether-modified, chiral N- salicylidene vanadyl (V) tert-leucinates onto 4-azidomethyl-substituted polystyrene by click chemistry was examined. Among the eight different solvents investigated, the resulting polystyrene-supported catalysts promote the asymmetric, aerobic oxidation of α-hydroxy (thio) esters and amides with enantioselectivities of up to 99% ee (selectivity factor up to ...