A Michael addition assisted by fluorapatite in heterogeneous media is described. Reaction between mercaptans and chalcone derivatives was studied at room temperature in methanol as solvent. By-products of usual undesirable reactions in Michael addition such as 1, 2-addition, bis-addition and polymerisation are not observed. The yields obtained are good to excellent.
![[(E)-4-Nitrostyryl]phenyl ketone Structure](https://image.chemsrc.com/caspic/073/2960-55-6.png)
![ethyl 2-[1-(4-nitrophenyl)-3-oxo-3-phenylpropyl]sulfanylacetate Structure](https://image.chemsrc.com/caspic/340/55483-99-3.png)