The derivatives of thienopyrimidine have been the focus of great interest over many years. This is probably due to their biological properties, [ 1-5 View all references ] such as antiviral, antifungal, insecticidal, antibacterial, and antiparasitic properties, and medicinal applications as inhibitors of VEGFR-2 [ 6 6. Munchhof , MJ ; Beebe , JS ; Casavant , JM ; Cooper , BA ; Doty , JL ; Higdon , RC ; Hillerman , SM ; Soderstrom , CI ; Knauth , EA ; Marx , MA ; Rossi , ...