Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: structure-activity relation study of matrine-type alkaloids.

S Kobashi, H Kubo, T Yamauchi…

Index: Biological and Pharmaceutical Bulletin, , vol. 25, # 8 p. 1030 - 1034

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Citation Number: 18

Abstract

... e-mail: kimio@hoshi.ac.jp © 2002 Pharmaceutical Society of Japan ... Acetic Acid-Induced Abdominal Contraction Assay (Writhing Test) Each mouse was injected ip with 0.7% acetic acid in a volume of 10 ml/kg 30 min after administra- tion of the test drugs (10—100 mg/kg). ... Vol. ...