Nuclear Medicine Communications 1986-01-01

The biodistribution of 67Ga-labelled N-hydroxyamino acid derivatives in tumour-bearing rats.

J D Herscheid, G H Knops, M Hoekstra

Index: Nucl. Med. Commun. 7(1) , 53-7, (1986)

Full Text: HTML

Abstract

The biodistribution of 67Ga-labelled complexes of some mono- and di-N-hydroxyamino acid derivatives and of two siderophores (trihydroxamates) were evaluated in Rhabdomyosarcoma-bearing rats. It was found that the mono- and dihydroxamates could not enhance the tumour-localizing properties of 67Ga-citrate, while the 67Ga-labelled trihydroxamates showed very rapid urinary excretion.