A Comparative Study of the Synthesis of 3??Substituted Catechols using an Enzymatic and a Chemoenzymatic Method

V Berberian, CCR Allen, ND Sharma…

Index: Berberian; Allen; Sharma; Boyd; Hardacre Advanced Synthesis and Catalysis, 2007 , vol. 349, # 4-5 p. 727 - 739

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Citation Number: 25

Abstract

Abstract A series of cis-dihydrodiol metabolites, available from the bacterial dioxygenase- catalysed oxidation of monosubstituted benzene substrates using Pseudomonas putida UV4, have been converted to the corresponding catechols using both a heterogeneous catalyst (Pd/C) and a naphthalene cis-diol dehydrogenase enzyme present in whole cells of the recombinant strain Escherichia coli DH5α (pUC129: nar B). A comparative study of the ...