Synthesis

Perchloric acid adsorbed on silica gel (HClO4-SiO2) as an inexpensive, extremely efficient, and reusable dual catalyst system for acetal/ketal formation and their …

R Kumar, D Kumar, AK Chakraborti

Index: Kumar, Raj; Kumar, Dinesh; Chakraborti, Asit K. Synthesis, 2007 , # 2 p. 299 - 303

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Citation Number: 35

Abstract

Abstract Perchloric acid adsorbed on silica gel (HClO 4-SiO 2) is reported as extremely efficient, inexpensive, and reusable catalyst for dual role for protection of aldehydes/ketones (with trialkyl orthoformates) as acetals/ketals and deprotection (with water-alcohol) to regenerate the carbonyl compounds in high yields at room temperature and in short times. Acetalization/ketalization of electrophilic aldehydes/ketones was carried out under solvent ...