Organic & Biomolecular Chemistry 2004-04-21

Cytosine-substituted metalloporphyrins: receptors for recognition of nucleotides in ion-selective electrodes.

Vladimír Král, Tatiana V Shishkanova, Jonathan L Sessler, Christopher T Brown

Index: Org. Biomol. Chem. 2(8) , 1169-75, (2004)

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Abstract

A new series of cytosine-substituted metalloporphyrin conjugates (containing Co(II) and Zn(II) as the coordinated metals) were designed and investigated as nucleotide receptors in PVC-membrane-based ion-selective electrodes under neutral conditions. The potentiometric results indicate that these systems, in particular the Co(II)-containing complex, may be potentially useful sensors for complementary nucleotide substrates in the presence of 10 mol% tridodecylmethylammonium chloride (K(Pot.)(5'-GMP/5'-AMP)= 0.045).