Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1989-07-01

[Inhibitory effect of inositol hexasulfate and inositol hexaphosphoric acid (phytic acid) on the proliferation of the human immunodeficiency virus (HIV) in vitro].

T Otake, H Shimonaka, M Kanai, K Miyano, N Ueba, N Kunita, T Kurimura

Index: Kansenshōgaku Zasshi. 63(7) , 676-83, (1989)

Full Text: HTML

Abstract

The monosaccharide substances inositol hexasulfate (IHS) and inositol hexaphosphoric acid (Phytic acid, IHP) were investigated for their antiviral effect on the human immunodeficiency virus (HIV) in vitro. In MT-4 cells IHS completely inhibited the cytopathic effect of HIV and the HIV specific antigen expression at a concentration of 1.67 mg/ml. IHP moderately inhibited both of HIV effects as mentioned above.