Irish Journal of Medical Science 1999-01-01

Efficacy of a new quarternary ammonium compound against TB.

C Byrne, T M Healy

Index: Ir. J. Med. Sci. 168(1) , 45-6, (1999)

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Abstract

Ten of 12 strains of Mycobacteria (11 M. tuberculosis, 1 M. bovis) including 7 resistant strains were found to be sensitive to tetradecyl-dimethyl-benzyl-ammonium fluoride (TDBAF) at a concentration of 15-7.75 micrograms/ml (end point 10 micrograms/ml). A single multi-resistant strain of M. tuberculosis and a culture of M. bovis were also sensitive but at a slightly higher level.