Diabetes Research and Clinical Practice 2011-08-01

DPP-IV inhibitor may affect spermatogenesis.

Hatsuki Hibi, Tadashi Ohori, Yoshiaki Yamada

Index: Diabetes Res. Clin. Pract. 93(2) , e74-5, (2011)

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Abstract

A 39-year-old physician was diagnosed retrograde ejaculation due to diabetes and treated with amoxapine. This treatment was effective; he could ejaculate. He began receiving DPP-IV inhibitor (Sitagliptin 50 mg, daily), in lieu of insulin injection. Unusual effect on semen quality was occurred following the administration of the drug.Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.