Water soluble phosphines: Part XIII. Chiral phosphine ligands with amino acid moieties

…, M Tepper, O Stelzer, T Häusler, WS Sheldrick

Index: Brauer, David J.; Schenk, Stefan; Rossenbach, Stefan; Tepper, Michael; Stelzer, Othmar; Haeusler, Thomas; Sheldrick, William S. Journal of Organometallic Chemistry, 2000 , vol. 598, # 1 p. 116 - 126

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Citation Number: 34

Abstract

Nucleophilic phosphination of the potassium or sodium salt of the fluorophenylalanines (1a, 2a) or-glycines (3a, 4a) with potassium phosphides Ph (R) PK (R= Me, Ph) yields chiral phosphine ligands (1–7) with amino acid moieties. The X-ray structure of 3· 2H2O (space group Pbca) has been determined showing a betaine type structure for the amino acid moiety. The α-methyl derivatives of the phosphinophenylglycines (10, 11) were obtained ...