International Journal of Pharmaceutics 2002-03-20

Dynamic mechanical thermal analysis studies of polymer films prepared from aqueous dispersion.

S V Lafferty, J M Newton, F Podczeck

Index: Int. J. Pharm. 235(1-2) , 107-11, (2002)

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Abstract

Dynamic Mechanical Thermal Analysis of cast and sprayed films of an aqueous dispersion of polymethyl methacrylate (Eudragit NE30D) and mixtures with an aqueous dispersion of ethylcellulose (Aquacoat ECD-30) has been undertaken. Such analysis allows the identification of glass transition temperatures and the degree of miscibility of the polymers. It was found that the two polymers formed as cast or sprayed films were not miscible but had an optimal composition of 30% of the ethylcellulose dispersion in the polymethyl methacrylate dispersion.