Facile and green syntheses of novel 2-(1, 2-benzisothiazole-3-one-1, 1-dioxide)-N- arylacetamides, 2-(1, 3-dioxoisoindolin-2-yl)-N-arylacetamides and 2-(N-(2-oxo-2- (arylamino) ethyl) sulfamoyl (or) carbamoyl) benzoic acids have been developed and tested for their biological activities against Baccilus megaterieum, Escherichia coli, Providencia stuartii, Pseudomonas putida. Some of the synthesized compounds possess good activity ...