Synthetic Communications

One-Pot Multicomponent Condensation Reaction of Aldehydes with Cyclic Ketones

P Wu, XM Cai, QF Wang, CG Yan

Index: Wu, Ping; Cai, Xi-Mei; Wang, Qi-Fang; Yan, Chao-Guo Synthetic Communications, 2011 , vol. 41, # 6 p. 841 - 850

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Citation Number: 7

Abstract

Abstract Under microwave irradiation, the one-pot multicomponent condensation reaction of three molar aromatic aldehydes with two molar cyclic ketones having free α, α′-methylene positions such as cyclopentanone or cyclohexanone in the presence of ammonium acetate and acetic acid afforded dicyclocalkenopyridines with two α-arylidene groups in good yields. In similar reaction conditions, 1-tetralone, which has only one α-methylene position, ...