Journal of Cardiovascular Electrophysiology 1998-11-01

ST segment elevation induced by class IC antiarrhythmic agents: underlying electrophysiologic mechanisms and insights into drug-induced proarrhythmia.

S C Krishnan, M E Josephson

Index: J. Cardiovasc. Electrophysiol. 9(11) , 1167-72, (1998)

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Abstract

Three patients in whom Class IC sodium channel blockers induced ST segment elevation in leads V1 through V3 are described. The underlying electrophysiologic mechanism, implications for drug-induced proarrhythmia, and the relationship of the finding to the Brugada syndrome type of idiopathic ventricular fibrillation are discussed.