Synlett

Carboxylic phosphoric anhydrides as a new coupling partner in Pd-catalyzed coupling reactions: A new ketone synthesis

KC Lim, YT Hong, S Kim

Index: Lim, Kyoung-Chan; Hong, Young-Taek; Kim, Sunggak Synlett, 2006 , # 12 p. 1851 - 1854

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Citation Number: 3

Abstract

Abstract The Pd-catalyzed cross-coupling reactions of carboxylic phosphoric anhydrides with organoboronic acids or organostannanes afforded the corresponding ketones. The intramolecular Heck reaction was successful with carboxylic phosphoric anhydrides as a coupling partner.

~88%

~45%

~66%

~89%

~54%

~81%

~84%

~72%

~75%

~72%

5-Phenyl substituted 1-methyl-2-pyridones and 4′-substituted...

[Picard, Franck; Schulz, Tobias; Hartmann, Rolf W. Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 2 p. 437 - 448]