Preparation and characterization of bicyclic amide acetals and monothioacetals

…, RT Gallant, MC Jennings

Index: Guthrie, J. Peter; Gallant, Roger T.; Jennings, Michael C. Canadian Journal of Chemistry, 2004 , vol. 82, # 2 p. 268 - 278

Full Text: HTML

Citation Number: 2

Abstract

We have prepared and characterized new examples of 5-substituted-1-aza-4, 6- dioxabicyclo [3.3. 0] octanes (bicyclic amide acetals) and examples of the new heterocyclic system, 5-substituted-1-aza-4-oxa-6-thiabicyclo [3.3. 0] octanes (bicyclic amide monothioacetals). Detailed analysis of NMR coupling constants and X-ray structure determination for an example of each class of compound established the stereochemistry ...