Organic Letters 2003-05-29

Total synthesis of (+)-strictifolione.

Samir BouzBouz, Janine Cossy

Index: Org. Lett. 5(11) , 1995-7, (2003)

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Abstract

[reaction: see text] The synthesis of (+)-strictifolione was achieved from 3-phenylproprionaldehyde by using enantioselective allyltitanations to control the stereogenic centers at C6, C4', and C6' and a cross-methathesis to control the configuration of the double bond at C1'-C2'.