Synthesis and evaluation of phenoxyoxazaphospholidine, phenoxyoxazaphosphinane, and benzodioxaphosphininamine sulfides and related compounds as …

C Mara, E Dempsey, A Bell, JW Barlow

Index: Mara, Christine; Dempsey, Enda; Bell, Angus; Barlow, James W. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 12 p. 3580 - 3583

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Citation Number: 5

Abstract

A series of phenoxyoxazaphospholidine, phenoxyoxazaphosphinane and benzodioxaphosphininamine sulfides and related cyclic organophosphorus compounds based on the lead anti-tubulin herbicides amiprophos methyl and butamifos were synthesised and evaluated for anti-malarial activity. Of these compounds, while none of the phenoxyoxazaphospholidines, phenoxyoxazaphosphinanes or ...