Chemical Communications 2007-06-21

Alkynylation of alpha-halocarbonyl compounds--a stille-type cross-coupling for the formation of C(sp)-C(sp3) bonds under neutral conditions.

Wei Shi, Chao Liu, Zai Yu, Aiwen Lei

Index: Chem. Commun. (Camb.) , 2342, (2007)

Full Text: HTML

Abstract

A direct alkynylation of readily available alpha-halo esters and amides with high yields is described herein; a distinct switch from diyne formation to alkynylation products was attained under neutral conditions.