Synthesis of 6-substituted thieno [3, 2-b] pyrroles

RL Keener, FS Skelton, HR Snyder

Index: Keener,R.L. et al. Journal of Organic Chemistry, 1968 , vol. 33, # 4 p. 1355 - 1359

Full Text: HTML

Citation Number: 8

Abstract

The synthetic pathway to 5-carbethoxythieno [3, 2-b] pyrrole has been improved and a new product isolated from its reaction with formaldehyde and dimethylamine. Several 6- substituted 5-carbethoxythieno [3, 2-b] pyrrole Compounds have been hydrolyzed and decarboxylated under mild conditions to afford important intermediates for the preparation of thieno [3, 2-b] pyrrole analogs of natural indole compounds.