Tetrahedron letters

A new synthesis of polycyclic aromatic hydrocarbons via titanium (IV)-catalyzed aldol-type condensation of silyl enol ethers with 2-arylacetaldehydes

P Di Raddo, RG Harvey

Index: Raddo, Pasquale Di; Harvey, Ronald G. Tetrahedron Letters, 1988 , vol. 29, # 32 p. 3885 - 3886

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Citation Number: 10

Abstract

Polycyclic aromatic hydrocarbons (polyarenes) are widely distributed environmental pollutants many of which exhibit carcinogenic activity. 1 However, methods for the synthesis of polyarenes have failed to keep pace with the rapidly expanding research interest in the chemistry and biological properties of molecules of this class. Many of the synthetic methods currently in use have a venerable history, dating back to the 1930s or even earlier.2 We now report a convenient new ...