One step synthesis of pyrimido [1, 2??a][1, 8] naphthyridinones, pyrido [1, 2??a] pyrimidinones and 1, 8??naphthyridinones. Antihypertensive agents. V

PL Ferrarini, C Mori, G Primofiore…

Index: Ferrarini, Pier Luigi; Mori, Claudio; Primofiore, Giampaolo; Calzolari, Lorella Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 4 p. 881 - 886

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Citation Number: 34

Abstract

Abstract The condensation of 2, 6-diaminopyridine and 2-acetamido-6-aminopyridine with β- keto esters in polyphosphophoric acid was studied. In this reaction some 1, 8- naphthyridinones, pyrido [1, 2-a] pyrimidinones and pyrimido [1, 2-a][1, 8] naphthyridinones variously substituted were obtained.