Abstract Effective methods for the introduction of the short-lived positron-emitter fluorine-18 (t 1/2= 109.7 min) at high specific radioactivity into fluoroarenes are valuable for the development of radiotracers for molecular imaging with positron emission tomography. We have explored the scope of the radiofluorination of diaryliodonium salts with no-carrier- added (NCA)[18 F] fluoride ion for the preparation of otherwise difficult to access meta- ...