e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
A new approach to the construction of biphenylenes by the cobalt-catalyzed cocyclization of o-diethynylbenzenes with alkynes. Application to an iterative approach to [ …
BC Berris, GH Hovakeemian, YH Lai…
Index: Berries,B.C.; Hovakeemian,G.H.; Lai,Y.H. Journal of the American Chemical Society, 1985 , vol. 107, p. 5670
Abstract: CpCo (CO), has been found to catalyze the cocyclization of o-diethynylbenzenes with alkynes to give 2, 3-disubstituted biphenylenes. This method has been applied to the total synthesis of [3] phenylene (3) and some silylated derivatives 4 and 5. The spectral, chemical, and structural data indicate this system to be a highly unusual “ benzocyclobutadienoid” hydrocarbon framework containing [4n+ 21 7 electrons. The ...
