Organic & Biomolecular Chemistry 2011-10-07

Control of chemoselectivity in Dieckmann ring closures leading to tetramic acids.

Yong-Chul Jeong, Muhammad Anwar, Tuan Minh Nguyen, Benjamin Song Wei Tan, Christina Li Lin Chai, Mark G Moloney

Index: Org. Biomol. Chem. 9 , 6663, (2011)

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Abstract

An efficient strategy for the control of the chemoselectivity in Dieckmann ring closures leading to tetramic acids derived from serine and α-methyl serine is reported, and this provides pathways to diversely substituted systems from a common starting material.