Journal of Antibiotics 1985-12-01

Synthesis and biological activity of (7S)-O-epoxyalkyl derivatives of daunomycinone.

V Prikrylová, H Lipavská, J V Jizba, J Fuska, M Podojil, Z Vanĕk

Index: J. Antibiot. 38(12) , 1714-8, (1985)

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Abstract

Synthesis and antibacterial activity of a number of 7-O-epoxyalkyl derivatives of daunomycinone prepared from 7-O-alkenyl derivatives of daunomycinone are described along with their inhibitory effect on leukemia P 388 cells.