e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

2, 6-Difluorophenol as a bioisostere of a carboxylic acid: bioisosteric analogues of γ-aminobutyric acid

J Qiu, SH Stevenson, MJ O'Beirn…

Index: Journal of Medicinal Chemistry, , vol. 42, # 2 p. 329 - 332

Full Text: HTML

Citation Number: 30

Abstract

... Journal of Medicinal Chemistry. ... Departments of Chemistry and of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208-3113. J. Med. Chem. , 1999, 42 (2), pp 329–332. ...

2,6-Difluorophenol Structure

2,6-Difluorophenol

~%

2,4-Difluoro-3-methoxybenzonitrile Structure

2,4-Difluoro-3-...

2,6-Difluoro-4-Nitroanisole Structure

2,6-Difluoro-4-...

~%

2,4-Difluoro-3-methoxybenzonitrile Structure

2,4-Difluoro-3-...

3,5-Difluoro-4-methoxyaniline Structure

3,5-Difluoro-4-...

~%

2,4-Difluoro-3-methoxybenzonitrile Structure

2,4-Difluoro-3-...

3,5-difluoro-2-iodo-4-methoxyaniline Structure

3,5-difluoro-2-...

~%

2,4-Difluoro-3-methoxybenzonitrile Structure

2,4-Difluoro-3-...

2,6-Difluoro-4-nitrophenol Structure

2,6-Difluoro-4-...

~%

2,4-Difluoro-3-methoxybenzonitrile Structure

2,4-Difluoro-3-...

2,6-Difluoro-4-nitrophenol Structure

2,6-Difluoro-4-...

~%

4-Amino-2,6-difluorophenol Structure

4-Amino-2,6-dif...

2,6-Difluorophenol Structure

2,6-Difluorophenol

~%

4-Amino-2,6-difluorophenol Structure

4-Amino-2,6-dif...

2,6-Difluorophenol Structure

2,6-Difluorophenol

~%

3,5-Difluoro-4-methoxyaniline Structure

3,5-Difluoro-4-...

2,6-Difluoro-4-nitrophenol Structure

2,6-Difluoro-4-...

~%

3,5-Difluoro-4-methoxyaniline Structure

3,5-Difluoro-4-...