Acta Cardiologica 2006-12-01

Celiprolol-induced lupus-like syndrome.

Jean-Christophe Charniot, Thierry Genereau, Luc Mouthon

Index: Acta Cardiol. 61(6) , 661-3, (2006)

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Abstract

Systemic lupus erythematosus can be idiopathic or drug-induced. Although a number of beta-blockers have been reported to induce a lupus-like syndrome, to the best of our knowledge, no such case has been described following celiprolol therapy. We diagnosed a lupus-like syndrome in a 67-year-old female patient who developed febrile polyarthritis, percarditis, antinuclear and anti-histone antibodies after taking celiprolol for 2 years. Despite drug withdrawal, prolonged corticotherapy was needed to obtain clinical and biological remission.