Pest Management Science 2002-03-01

Synthesis and structure-activity relationships of benzophenone hydrazone derivatives with insecticidal activity.

Jason Smith, Ian Greaves

Index: Pest Manag. Sci. 2nd ed., 57 , 191-202, (2001)

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Abstract

A broad range of benzophenone hydrazone derivatives was prepared and tested against selected chewing insect pests, allowing the analysis of structure-activity relationships. Good activity was found only when the aromatic rings were substituted at the 4-positions with an halogen atom and a triflate or perhaloalkoxy group. In contrast, a number of substituents on the hydrazone part led to active compounds, the best results being achieved with acyl-type substituents. The excellent laboratory and greenhouse activity of the best representatives was confirmed in semi-field trials against Spodoptera littoralis.