Tetrahedron

Hydroxylated pyrrolidines. Synthesis of 1, 4-dideoxy-1, 4-imino-L-lyxitol, 1, 4, 5-trideoxy-1, 4-imino-D-and-L-lyxo-hexitol, 2, 3, 6-trideoxy-3, 6-imino-D-glycero-L-altro- …

DK Thompson, CN Hubert, RH Wightman

Index: Thompson, Deryk K.; Hubert, Christine N.; Wightman, Richard H. Tetrahedron, 1993 , vol. 49, # 18 p. 3827 - 3840

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Citation Number: 82

Abstract

Enantiospecific syntheses are reported for the title pyrrolidines, from carbohydrate precursors. An intermediate in one of the routes, ethyl 2, 3, 6-trideoxy-3, 6-imino-4, 5: 7, 8-di- O-isopropylidene-D-glycero-L-altro-octonate (23), could be converted in two steps into a β- lactam.