Organic Letters 2005-04-28

Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin- 5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one.

Prakash G Jagtap, Erkan Baloglu, Garry Southan, William Williams, Aloka Roy, Alexander Nivorozhkin, Nelson Landrau, Kevin Desisto, Andrew L Salzman, Csaba Szabó

Index: Org. Lett. 7(9) , 1753-6, (2005)

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Abstract

[reaction: see text] The synthesis of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-ones from the base-promoted condensation reaction of homophthalic anhydride and 2-(bromomethyl)-benzonitrile and a convenient method for the synthesis of indolo[3,2-c]isoquinolinones are described.