Synthetic communications

An efficient and environment friendly procedure for the synthesis of arylmethylenemalononitrile catalyzed by strong base anion??exchange resin in water

TS Jin, JS Zhang, AQ Wang, TS Li

Index: Jin, Tong-Shou; Zhang, Jian-She; Wang, Ai-Qing; Li, Tong-Shuang Synthetic Communications, 2004 , vol. 34, # 14 p. 2611 - 2616

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Citation Number: 31

Abstract

Arylmethylenemalononitrile is an important precursor of potentially bioactive pyrimidine derivatives.11. Quiroga , J. , Alvarado , M. , Insuatry , B. and Moreno , R. 1999. J. Heterocyclic Chem., 36: 1311 [CrossRef], [Web of Science ®] View all references Preparation of arylmethylenemalononitrile by the conventional method is completed via Knoevenagel condensation between malononitrile and various aromatic aldelhydes using organic bases (primary, secondary and tertiary ...